cellular immune responses in sheep against glutathione s-transferase of fasciola gigantica

Cellular Immune Responses in Sheep against Glutathione S-transferase of Fasciola gigantica

Seroprevalence of Fasciola gigantica infection in sheep in Khouzestan province, Southwest of Iran

Tropical fasciolosis is regarded as one of the most important helminthic infections of ruminants in Asia and Africa. Throughout most of its geographical range, Fasciola gigantica is of great importance as a parasite in sheep. The aim of this study was to detect seroprevalence of fascioliasis in sheep in Khouzestan province. In this study, due to the importance of livestock dise...

Comparison of humoral response in sheep to Fasciola hepatica and Fasciola gigantica experimental infection.

Humoral response of sheep to F. gigantica was compared with the well known humoral response to F. hepatica, in order to explain the difference of susceptibility of sheep to these two parasites. In this work, a lesser susceptibility of sheep to F. gigantica than to F. hepatica infection was confirmed. Humoral response to F. hepatica infection is similar to that previously described by several au...

Inhibition Assay Study of Purified Glutathione S-transferase from Fasciola Hepatica and Sheep Liver Tissue by Hexachlorophene

Glutathione S-transferases (GSTs) are widespread in Fasciola. hepatica parasite and sheep liver tissue. Study of GSTs inhibition assays in F. hepatica and sheep liver tissue are a priority of chemotherapeutic targets in parasitic liver diseases including human fascioliasis in Iran. In this research, the whole extract of F. hepatica and sheep liver tissues were purified and eluted for sodium dod...

The efficiency of diamphenethide against Fasciola hepatica in sheep

Specific antibody immune response against the parasitic portion of a glutathione-S-transferase fusion protein.

The humoral immune response against an Entamoeba histolytica recombinant protein has been investigated. The 628 bp Bam HI-Eco RI DNA fragment (L1b) from the M11 cDNA clone, partially coding for a 220 kDa (L220) protein, was ligated in-frame into the pGEX-3X plasmid vector to produce the fusion protein GST-L1b. BALB/c mice were immunized with different doses of the GST-L1b fusion protein (10-500...